The drug of choice will depend on the primary diagnosis, seizure type, effigy of the drug and the patient’s tolerance of treatment.
If a drug fails to control the seizures after it has been used in full therapeutic dosage for an adequate period, or if it is not tolerated, it should be gradually substituted with another drug, with the fist drug being withdrawn only when the new regimen is established.
If monotherpy is ineffective, next alternative drug should be started, and try to withdraw fist drug if there was no response for that drug or continue with that if there was partial response for initial drug.
Initial dose of the drug of choice should be determined on the basis of the degree of urgency, the size and age of the patient.
It should be increased gradually until an effective response is obtained. All antiepileptic commonly produce neurological adverse effects at higher dose ranges and patients should be monitored closely for adverse effects to help in accurate dose terrain.
Patients should ideally remain under supervision throughout treatment period.
Some major types of Anticonvulsants available with are as follows.
Carbamazepine Clobazam Clonazepam Diazepam Fosphenytoin Gabapenti Lamotrigine Levetiacetam Magnesium Sulphate Ox-carbamazepine Phenobarbitone Phenytoin Sodium Valproate Topiramate
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