A Brief About : Analgesics, Antipyretic, Non-Steroidal, Anti Inflammatory Drugs

A Brief About Analgesics, Antipyretic, Non-Steroidal, Anti Inflammatory Drugs- JIGSCHEMICAL

  1. Analgesics are used to relieve/reduce body pain and antipyretic are used to reduce elevated body temperature. Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever
  2. Non opioid analgesics are particularly suitable for relieving or management of pain in musculoskeletal conditions whereas the opioid analgesics are more suitable for moderate to severe visceral pain. Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system. Buprenorphine is a partial agonist of the μ-opioid receptor, and tramadol is a serotonin nor-epinephrine reuptake inhibitor.
  3. Those non-opioid analgesics which also have anti-inflammatory actins include salicylates and NSAIDs; they can reduce both pain and inflammation of chronic inflammatory disorders such as rheumatoid arthritis, but they do not alter or modify the disease process itself.
  4. For the management of rheumatoid arthritis, DMARDs (disease-modifying anti rheumatic drugs) may favourably influence the outcome of the disease.
  5. The pain and inflammation of an acute attack of gout is treated with a NSAID or colchicines; a xanthenes oxidises inhibitor is used for long-term control of gout. aspirin, ibuprofen and naproxen
  6. Neurogenic pain generally responds poorly to conventional analgesics; treatment can be difficult and includes the use of
    carbamazepine for trigeminal neuralgia.
  7. Effects of analgesics, such as using hydroxyzine, promethazine, carisoprodol, or tripelennamine to increase the pain-killing ability of a given dose of opioid analgesic.

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